University of Dayton
Academic Catalog 2013-14

Chemistry

Majors:

Minor:

The B.S. program in chemistry is approved by the American Chemical Society for the training of professional chemists. Students in the B.S. program in chemistry may choose to conduct an original research project which normally begins with the selection of a research professor and project during the first term of the junior year. The research project may be conducted over the entire senior year, and normally requires two work periods of three to four hours each a week. Alternatively, it may be conducted over a ten-week period during the summer following the junior year. In either case, the project culminates in the final term of the senior year with enrollment in CHM 498, the submission of an acceptable thesis, and the presentation of a seminar in CHM 497. Additional research work to a maximum total of six semester hours may be elected provided that the work extends beyond two semesters.

The B.S. program in biochemistry follows a curriculum which satisfies the needs of students who anticipate careers in the life sciences. Students in the B.S. program in biochemistry may choose to conduct an original research project in biochemistry or a related chemical sub-discipline. In all other respects these biochemically-related research projects are identical to those detailed for the B.S. in chemistry above.

The B.S. program in medicinal-pharmaceutical chemistry is designed to serve students who desire a more focused preparation in the analysis and synthesis of compounds of pharmacological significance. The program also provides a solid foundation for further studies in medicine, pharmacy or forensic chemistry. Students in the B.S. program in medicinal and pharmaceutical chemistry may choose to conduct an original research project, typically in synthetic or analytical chemistry. In all other respects these research projects are identical to those detailed for the B.S. in chemistry above.

The B.A. program in chemistry provides a curriculum which prepares students for a wide range of interdisciplinary professions. The traditional B.S. curriculum has been modified in the B.A. program, most notably in mathematics, physics, and advanced chemistry. The program is sufficiently flexible to afford a wide selection of courses in the humanities. Science courses may be chosen to provide a preparation for professions such as medicine, dentistry, optometry, veterinary medicine, biochemistry, education, and law, as well as for employment in many other areas which require a background in science.

A minor in chemistry consists of twenty semester hours.

Faculty

Mark B. Masthay, Chairperson
Professors Emeriti: Fratini, Keil, Knachel, Morrow, Singer
Associate Professors: Benin, Church, Johnson, Lopper, Masthay, S. Swavey
Assistant Professors: Crosson, Mammana
Visiting Assistant Professor: Trohalaki, Turner
Lecturer: Trick
Lab Instructors: Eckerle, Hils, Piepgrass, R. Swavey

 

Bachelor of Arts with a major in Chemistry (chm) Minimum 124 Hours

Common Academic Program (CAP)
*credit hours will vary depending on courses selected
First-Year Humanities Commons 112
The West & the World
Introduction to Religioius & Theological Studies
Introduction to Philosophy
Writing Seminar I 2
Second-Year Writing Seminar 30-3
Writing Seminar II
Oral Communication 3
Principles of Oral Communication
Mathematics 3
Social Science3
Arts3
Natural Sciences7
Crossing Boundariesvariable credit
Faith Traditions
Practical Ethical Action
Inquiry
Integrative
Advanced Studyvariable credit
Philosophy and/or Religious Studies
Historical Studies
Diversity and Social Justice3
Major Capstone0-3

1

 Completed with ASI 110 and ASI 120.

2

Or ENG 100A and ENG 100B, or ENG 200H, by placement.

3

 Completed with ENG 200H or ASI 120.



Liberal Studies Curriculum
Creative and Performing Arts (May include CAP Arts)3
L2 Proficiency (Proficiency in a language other than English)0-11
Literature (May include CAP Components)3
Mathematics (Satisfies CAP Mathematics)9
Introductory Calc I
   and Introductory Calc II
Statistical Meth I
Natural Sciences (Applies to CAP Natural Science)8
PHY 201
  & 201L
General Physics
   and General Physics Lab
PHY 202
  & 202L
General Physics
   and General Physics Lab
Social Sciences (Includes CAP Social Science)12

Major Requirements 136
(CHM 123 applies to CAP Natural Science)
CHM 123
  & 123L
General Chemistry
   and Gen Chemistry Lab
4
CHM 124
  & 124L
General Chemistry
   and Gen Chemistry Lab
4
CHM 201
  & 201L
Quantitative Anal
   and Quant Analysis Lab
4
CHM 302Physical Chemistry3-6
or CHM 303
  & CHM 304
Physical Chemistry
   and Physical Chemistry
CHM 313
  & 313L
Organic Chemistry
   and Organic Chemistry Lab
4
CHM 314
  & 314L
Organic Chemistry
   and Organic Chem Lab
4
CHM 496Prof Practice Seminr (Satisfies CAP Major Capstone)0
Select four courses from: 210-13
Spectro Idn-Org Cmpd
Environmental Chem
Topics-Physical Chm
Intermed Organic Chm
Analytical Chemistry
Analytical Chem Lab
Inorganic Chemistry
Inorganic Chem Lab
Biochemistry
Biosynthetic Org Chm
Medicinal Chemistry
Gen Biochemistry I
Gen Biochemistry II
Biochemistry Lab
Honors Thesis
Honors Thesis
Research Seminar
   and Research & Thesis
Research & Thesis

Breadth
ASI 150Intr to the Univ Exp1
Total Hours to total at least124

1

 Advanced placement is permitted.

2

 May substitute two upper level courses from other science departments with permission of chairperson.


 

Bachelor of Science with a major in Biochemistry (bcm) Minimum 120 Hours

Common Academic Program (CAP)
*credit hours will vary depending on courses selected
First-Year Humanities Commons 112
The West & the World
Introduction to Religioius & Theological Studies
Introduction to Philosophy
Writing Seminar I 2
Second-Year Writing Seminar 30-3
Writing Seminar II
Oral Communication 3
Principles of Oral Communication
Mathematics 3
Social Science3
Arts3
Natural Sciences7
Crossing Boundariesvariable credit
Faith Traditions
Practical Ethical Action
Inquiry
Integrative
Advanced Studyvariable credit
Philosophy and/or Religious Studies
Historical Studies
Diversity and Social Justice3
Major Capstone0-3

1

 Completed with ASI 110 and ASI 120.

2

Or ENG 100A and ENG 100B, or ENG 200H, by placement.

3

 Completed with ENG 200H or ASI 120.



Science Breadth Requirements
CPS 132Progrmmng-Engr & Sci3
MTH 168Anly Geom & Calc I (Satisfies CAP Mathematics)4
MTH 169Anly Geom & Calc II4
MTH 218Anly Geom & Calc III4
PHY 206Gen Physics I Mech3
PHY 207Gen Phy II Ele & Mag3
PHY 201LGeneral Physics Lab1
Select courses from:10
General Genetics
Plant Biology
Physiology I
Physiology II
General Microbiology
Immunology
Cell Biology
Molecular Biology
Bio-Infectious Dis
Topics-Physical Chm
Intermed Organic Chm
CHM 415
  & 415L
Analytical Chemistry
   and Analytical Chem Lab
Inorganic Chemistry
Inorganic Chem Lab
Biosynthetic Org Chm
Medicinal Chemistry
Research Seminar
   and Research & Thesis
Research & Thesis

Major Requirements 145
Satisfies CAP Natural Science
Year 1
BIO 151
  & 151L
Concepts of Bio I
   and Concepts-Bio Lab I
4
BIO 152Concepts of Bio II3
CHM 123
  & 123L
General Chemistry
   and Gen Chemistry Lab
4
CHM 124
  & 124L
General Chemistry
   and Gen Chemistry Lab
4
Year 2
CHM 201
  & 201L
Quantitative Anal
   and Quant Analysis Lab
4
CHM 313
  & 313L
Organic Chemistry
   and Organic Chemistry Lab
4
CHM 314
  & 314L
Organic Chemistry
   and Organic Chem Lab
4
BIO Elective and Laboratory4
Year 3
CHM 303
  & 303L
Physical Chemistry
   and Physical Chem Lab
4
CHM 304Physical Chemistry3
CHM 451Gen Biochemistry I3
CHM 452Gen Biochemistry II3
CHM 462LBiochemistry Lab1
CHM 495Intro-Resrch Seminar0
Year 4
CHM 496Prof Practice Seminr (Satisfies CAP Major Capstone)0

Breadth
ASI 150Intr to the Univ Exp1
Foreign Language6-8
Social and Behavioral Sciences (Includes CAP Social Science)6
Total Hours to total at least120

1

 Advanced placement is permitted.



 

Bachelor of Science with a major in Chemistry (chm) Minimum 120 Hours

Common Academic Program (CAP)
*credit hours will vary depending on courses selected
First-Year Humanities Commons 112
The West & the World
Introduction to Religioius & Theological Studies
Introduction to Philosophy
Writing Seminar I 2
Second-Year Writing Seminar 30-3
Writing Seminar II
Oral Communication 3
Principles of Oral Communication
Mathematics 3
Social Science3
Arts3
Natural Sciences7
Crossing Boundariesvariable credit
Faith Traditions
Practical Ethical Action
Inquiry
Integrative
Advanced Studyvariable credit
Philosophy and/or Religious Studies
Historical Studies
Diversity and Social Justice3
Major Capstone0-3

1

 Completed with ASI 110 and ASI 120.

2

Or ENG 100A and ENG 100B, or ENG 200H, by placement.

3

 Completed with ENG 200H or ASI 120.



Science Breadth Requirements
Mathematics, Computer Sciences 115
Progrmmng-Engr & Sci
Anly Geom & Calc I (Satisfies CAP Mathematics)
Anly Geom & Calc II
Anly Geom & Calc III
PHY 206Gen Physics I Mech (Applies to CAP Natural Science)3
PHY 207Gen Phy II Ele & Mag3
PHY 208Gen Phy III Mec Wavs3
PHY 210LGen Physics Lab I1
PHY 211LGen Physics Lab II1

Major Requirements 249
Year 1
CHM 123
  & 123L
General Chemistry
   and Gen Chemistry Lab (Applies to CAP Natural Science)
4
CHM 124
  & 124L
General Chemistry
   and Gen Chemistry Lab
4
Year 2
CHM 201
  & 201L
Quantitative Anal
   and Quant Analysis Lab
4
CHM 313
  & 313L
Organic Chemistry
   and Organic Chemistry Lab
4
CHM 314
  & 314L
Organic Chemistry
   and Organic Chem Lab
4
Year 3
CHM 303
  & 303L
Physical Chemistry
   and Physical Chem Lab
4
CHM 304
  & 304L
Physical Chemistry
   and Physical Chem Lab
4
CHM 317Spectro Idn-Org Cmpd1
CHM 417Inorganic Chemistry3
CHM 418LInorganic Chem Lab1
CHM 495Intro-Resrch Seminar0
Year 4
CHM 415
  & 415L
Analytical Chemistry
   and Analytical Chem Lab
4
CHM 420Biochemistry3
or CHM 451
  & CHM 452
Gen Biochemistry I
   and Gen Biochemistry II
CHM 496Prof Practice Seminr (Satisfies CAP Major Capstone)0
Select three courses from: 39
Topics-Physical Chm
Intermed Organic Chm
Biosynthetic Org Chm
Medicinal Chemistry
Biochemistry Lab
Honors Thesis
Honors Thesis
Research Seminar
   and Research & Thesis
Research & Thesis

Breadth
ASI 150Intr to the Univ Exp1
Foreign Language6-8
Social and Behavioral Sciences (Includes CAP Social Science)6
Total Hours to total at least120

1

 Should be completed during the first two years.

2

 Advanced placement is permitted.

3

 May substitute one approved science course from another department.



 

Bachelor of Science in Medicinal-Pharmaceutical Chemistry (mcm) Minimum 120 hours

Common Academic Program (CAP)
*credit hours will vary depending on courses selected
First-Year Humanities Commons 112
The West & the World
Introduction to Religioius & Theological Studies
Introduction to Philosophy
Writing Seminar I 2
Second-Year Writing Seminar 30-3
Writing Seminar II
Oral Communication 3
Principles of Oral Communication
Mathematics 3
Social Science3
Arts3
Natural Sciences7
Crossing Boundariesvariable credit
Faith Traditions
Practical Ethical Action
Inquiry
Integrative
Advanced Studyvariable credit
Philosophy and/or Religious Studies
Historical Studies
Diversity and Social Justice3
Major Capstone0-3

1

 Completed with ASI 110 and ASI 120.

2

Or ENG 100A and ENG 100B, or ENG 200H, by placement.

3

 Completed with ENG 200H or ASI 120.



Science Breadth Requirements
Satisfies CAP Mathematics and CAP Natural Science
BIO 151
  & 151L
Concepts of Bio I
   and Concepts-Bio Lab I
4
BIO 152
  & 152L
Concepts of Bio II
   and Concepts-Bio Lab II
4
MTH 148
  & MTH 149
Introductory Calc I
   and Introductory Calc II
6
MTH 367Statistical Meth I3
PHY 201
  & 201L
General Physics
   and General Physics Lab
4
PHY 202
  & 202L
General Physics
   and General Physics Lab
4

Major Requirements 2, 353
Year 1
CHM 123
  & 123L
General Chemistry
   and Gen Chemistry Lab
4
CHM 124
  & 124L
General Chemistry
   and Gen Chemistry Lab
4
Year 2
CHM 201
  & 201L
Quantitative Anal
   and Quant Analysis Lab
4
CHM 313
  & 313L
Organic Chemistry
   and Organic Chemistry Lab
4
CHM 314
  & 314L
Organic Chemistry
   and Organic Chem Lab
4
Year 3
CHM 302
  & 302L
Physical Chemistry
   and Physical Chem Lab 1
4
CHM 317Spectro Idn-Org Cmpd1
CHM 420Biochemistry 43
CHM 462LBiochemistry Lab1
CHM 495Intro-Resrch Seminar0
Year 4
CHM 319LAdv Org Synthsis Lab1
CHM 426Biosynthetic Org Chm3
CHM 427Medicinal Chemistry3
CHM 454Rational Drug Design3
CHM 463LBioanalytical Chem Lab1
CHM 496Prof Practice Seminr (Satisfies CAP Major Capstone)0
Science Requirements13
Select six semester hours from: 5
Intermed Organic Chm
CHM 415
  & 415L
Analytical Chemistry
   and Analytical Chem Lab
Inorganic Chemistry
Inorganic Chem Lab
Research Seminar
   and Research & Thesis
Select two lecture courses and one laboratory from:
BIO 403
  & 403L
Physiology I
   and Physiology Lab
BIO 411
  & 411L
General Microbiology
   and Gen Microbiology Lab
BIO 440
  & 440L
Cell Biology
   and Cell Bio Lab

Breadth 6
ASI 150Intr to the Univ Exp1
Social and Behavioral Sciences (Includes CAP Social Science)6
Total Hours to total at least120

1

 Substitution of more advanced courses is possible upon consultation with the Department of Chemistry chairperson.

2

 Consult General Requirements for all Bachelor of Science programs and the Common Academic Program requirements.

3

 Advanced placement is permitted.

4

 Biochemistry courses CHM 451 and CHM 452 may be substituted, with CHM 452 counting as a general elective.

5

Chemistry graduate courses or advanced electives from other departments may be selected with the permission of the Department of Cehmistry chairperson.

6

If composition requirement is waived, the student should seek the English elective. Advanced writing courses are recommended. 


 

Minor in Chemistry (chm)

Chemistry
CHM 123
  & 123L
General Chemistry
   and Gen Chemistry Lab
4
CHM 124
  & 124L
General Chemistry
   and Gen Chemistry Lab
4
CHM 302Physical Chemistry3
or CHM 303 Physical Chemistry
Select three CHM courses (300/400 level) 19

1

 In consultation with the chairperson.


Courses

CHM 115. College Prepatory Chemistry. 3 Hours

One-term course for students desiring to enter a science or engineering program but whose background is insufficient for CHM 123 and CHM 124. Unacceptable for credit toward chemistry requirements in any chemistry program.

CHM 115L. College Prepatory Chemistry Laboratory. 1 Hour

Course to accompany CHM 115 or to be elected by students in CHM 200 who lack previous chemistry laboratory experience. One three-hour laboratory each week.

CHM 123. General Chemistry. 3 Hours

Comprehensive treatment of the fundamentals of general chemistry. Prerequisite(s): One year of high school chemistry or equivalent.

CHM 123L. General Chemistry Laboratory. 1 Hour

Laboratory course to complement CHM 123. One three-hour laboratory session each week. Corequisite(s): CHM 123.

CHM 124. General Chemistry. 3 Hours

Comprehensive treatment of the fundamentals of general chemistry. Prerequisite(s): CHM 123.

CHM 124L. General Chemistry Laboratory. 1 Hour

Laboratory course to complement CHM 124. One three-hour laboratory session each week. Prerequisite(s): CHM 123L Corequisite(s): CHM 124.

CHM 200. Chemistry & Society. 3 Hours

Course for nonscience majors. The application of chemical principles to the examination of issues such as environmental quality, disease, hunger, synthetic materials, and law enforcement. Depending upon background and experience, a student needing a laboratory course may enroll in either CHM 115L or CHM 123L. Prerequisite(s): One year of high school chemistry or equivalent.

CHM 201. Quantitative Analysis. 3 Hours

Application of the principles of chemical equilibrium to the theory and techniques of gravimetric, volumetric, spectrophotometric, and electroanalytical methods of chemical analysis. Prerequisite(s): CHM 124, CHM 124L.

CHM 201L. Quantitative Analysis Laboratory. 1 Hour

Course to accompany CHM 201. One three-hour laboratory period each week.

CHM 234. Energy Resources. 3 Hours

The chemical and geological aspects of formation, production, and benefits/costs (including environmental impacts) of energy derived from fossil fuels (coal and hydrocarbons), biofuels (e.g., ethanol production), radioactive materials (nuclear power), and renewable sources (e.g., geothermal, hydro, wind, and solar power). Prerequisite(s): CHM 123, CHM 124. Corequisite(s): GEO 208.

CHM 302. Physical Chemistry. 3 Hours

Essential elements of thermodynamics, chemical kinetics, equilibria, and electrochemistry for those with a primary interest in the life sciences. For B.A. chemistry majors and premedical, predental, and biology majors. Prerequisite(s): CHM 124.

CHM 302L. Physical Chemistry Laboratory. 1 Hour

Course to accompany CHM 302. One three-hour laboratory each week. Prerequisite(s): CHM 201, CHM 201L. Corequisite(s): CHM 302.

CHM 303. Physical Chemistry. 3 Hours

Fundamentals of thermodynamics, chemical kinetics, electrochemistry, and spectroscopy with a mathematics format. For B.S. chemistry and biochemistry majors and chemical engineers. Prerequisite(s): CHM 201 or equivalent. Corequisite(s): MTH 218.

CHM 303L. Physical Chemistry Laboratory. 1 Hour

Course to accompany CHM 303. One three-hour laboratory each week. Prerequisite(s): MTH 218.

CHM 304. Physical Chemistry. 3 Hours

Fundamentals of thermodynamics, chemical kinetics, electrochemistry, and spectroscopy with a mathematics format. For B.S. chemistry and biochemistry majors and chemical engineers.

CHM 304L. Physical Chemistry Laboratory. 1 Hour

Course to accompany CHM 304. One three-hour laboratory each week. Corequisite(s): MTH 218.

CHM 313. Organic Chemistry. 3 Hours

Major topics in organic chemistry including synthesis, mechanisms, stereochemistry, and spectroscopy. Required of all chemistry majors and students in the life sciences. Prerequisite(s): CHM 124.

CHM 313L. Organic Chemistry Laboratory. 1 Hour

Common separation, purification, and analytical techniques including chromatography and spectroscopy. One three-hour laboratory each week. Corequisite(s): CHM 313.

CHM 314. Organic Chemistry. 3 Hours

Major topics in organic chemistry including synthesis, mechanisms, stereochemistry, and spectroscopy. Required of all chemistry majors and students in the life sciences. Prerequisite(s): CHM 313.

CHM 314L. Organic Chemistry Laboratory. 1 Hour

Synthesis and characterization of organic materials utilizing skills from CHM 313L. One three-hour laboratory each week. Prerequisite(s): CHM 313L. Corequisite(s): CHM 314.

CHM 317. Spectroscopic Identification of Organic Compounds. 1 Hour

The use of nuclear magnetic resonance, infrared, and mass spectrometry in elucidating structures. Emphasis on interpretation and integration of spectral data in problem solving. Prerequisite(s): (CHM 314, CHM 314L) or equivalent.

CHM 319L. Advanced Organic Synthesis Laboratory. 1 Hour

Preparation of organic compounds by single and multi-step synthetic sequences. Basic techniques in synthesis including use of organometallics, inert atmosphere, temperature control, extraction, vacuum distillation, column chromatography, recrystallization, and spectroscopic characterization methods. One four-hour laboratory each week. Prerequisite(s): CHM 314, CHM 314L.

CHM 341. Environmental Chemistry. 3 Hours

An introduction to the chemical processes in the environment. Topics include chemical equilibrium in aqueous solution, reaction mechanisms as applied to atmospheric chemistry, and analytical methods commonly applied to environmental samples. Prerequisite(s): CHM 314 or permission of instructor.

CHM 341L. Environmental Chemistry Laboratory. 1 Hour

Laboratory course to accompany CHM 341. Corequisite(s): CHM 341.

CHM 404. Special Topics in Physical Chemistry. 3 Hours

Thorough treatment of topics such as electrochemistry, macromolecules, photochemistry, or spectroscopy. May be repeated as topics change. Prerequisite(s): CHM 302 or CHM 303.

CHM 412. Intermediate Organic Chemistry. 3 Hours

Modern theory and practice of organic chemistry. May include structure-reactivity relationships, reaction mechanism, and synthetic topics not normally treated in introductory courses. Prerequisite(s): CHM 302 or equivalent; CHM 313, CHM 314; senior standing.

CHM 415. Analytical Chemistry. 2 Hours

Chemical analysis based on modern instrumentation. Chromatographic, electrochemical, and spectroscopic methods. Prerequisite(s): CHM 201, CHM 201L; (CHM 302 or CHM 304).

CHM 415L. Analytical Chemistry Laboratory. 2 Hours

Course to accompany CHM 415. Two three-hour laboratory sessions each week. Prerequisite(s): CHM 201L; CHM 302 or equivalent.

CHM 417. Inorganic Chemistry. 3 Hours

An advanced course in modern inorganic chemistry. Atomic structure, principles of bonding and structure, acid-base chemistry, periodicity, coordination compounds, nonaqueous solvents, electrochemistry, molecular symmetry, organometallic compounds, and the chemistry of selected representative elements. Prerequisite(s): CHM 314. Corequisite(s): CHM 302 or CHM 304.

CHM 418L. Inorganic Chemistry Laboratory. 1 Hour

Laboratory course dealing with the synthesis and characterization of inorganic and organometallic compounds. Topics include vacuum and inert atmosphere techniques, separation and purification, spectroscopic characterization, X-ray diffraction, magnetic moment, and conductance measurements. Prerequisite(s): CHM 201L, CHM 314L. Corequisite(s): CHM 417.

CHM 420. Biochemistry. 3 Hours

The fundamental aspects of the chemistry and biochemistry of carbohydrates, lipids, proteins, and nucleic acids. Enzymology, protein purification, bioenergetics, metabolism of carbohydrates, lipids, amino acids, nucleotides and nucleic acids, elementary molecular biology, and control processes are described. Acceptable preparation for medical school. Prerequisite(s): CHM 314.

CHM 426. Biosynthetic Organic Chemistry. 3 Hours

Mechanistic fundamentals of the biosynthesis and transformation of organic natural products, with special emphasis on medicinal compounds, toxins, pheromones and other secondary metabolite structures. Prerequisite(s): (CHM 314, CHM 314L) or equivalent.

CHM 427. Medicinal Chemistry. 3 Hours

The chemical mechanisms of action of the major drug classes will be surveyed with particular emphasis on the facets of organic chemistry that control drug-receptor interactions, metabolism and mechanisms of toxicity and resistance. First term. Prerequisite(s): CHM 314; (CHM 420 or CHM 451).

CHM 450. Advanced Organic Synthesis. 3 Hours

Fundamentals of synthesis and transformations of organic compounds, with emphasis on mechanisms; pericyclic reactions; small and medium ring synthesis; chemoselectivity, regioselectivity, stereoselectivity, retrosynthesis, functional group transformations, carbon-carbon bond forming reactions, oxidations, reductions and protecting groups. Prerequisite: (CHM 314, CHM 314L) or equivalent.

CHM 451. General Biochemistry I. 3 Hours

Discussion of the chemistry and biochemistry of carbohydrates, amino acids, proteins, and nucleic acids, including health-science and methodologic aspects. Descriptions of enzymology, protein purification, and carbohydrate metabolism related to such topics as bioenergetics, membranes, and disease processes. Recommended for students desiring entry into graduate and professional schools. Prerequisite(s): CHM 201, CHM 314.

CHM 452. General Biochemistry II. 3 Hours

Discussion of selected topics in bioenergetics, and metabolism of lipids, amino acids, porphyrins, nucleic acids, and proteins. Current aspects of nutrition, biochemical genetics, endocrinology, regulation, and genetic engineering addressed and related to health-science topics as time permits. Suitable preparation for medical school. Prerequisite(s): CHM 451.

CHM 454. Rational Drug Design. 3 Hours

Introduction to drug target selection, lead compound discovery, and application of structure-activity relationships and computational chemistry towards refinement and optimization of lead compounds and their derivatives. Use of molecular graphics software and publicly available macromolecular structure databases will provide the foundation for evaluating macromolecular models of drug targets and allow a hands-on exploration of the structure/function relationships of proteins that have been successful targets of rational drug design. Prerequisite(s): (CHM 420 or CHM 452) or equivalent.

CHM 462L. Biochemistry Laboratory. 1 Hour

Laboratory course to accompany biochemistry lecture courses. Spectrophotometry, pH and dissociation, enzymologic methodology and analytical techniques, chromatographic techniques. Corequisite(s): CHM 420 or CHM 451.

CHM 463L. Bioanalytical Chemistry Laboratory. 1 Hour

Introduction to analytical methods in current use in biochemistry. Course will focus on separations and spectroscopic methods for the analysis of biomolecules. Prerequisite(s): CHM 201, CHM 201L, CHM 302.

CHM 477. Honors Thesis Project. 3 Hours

First of two courses leading to the selection, design, investigation, and completion of an independent, original Honors Thesis project under the guidance of a faculty research advisor. Restricted to students in the University Honors Program with permission of the program director and department chairperson. Students pursuing an interdisciplinary thesis topic may register for three semester hours each in two separate disciplines in consultation with the department chairpersons. Prerequisite(s): Approval of University Honors Program.

CHM 478. Honors Thesis Project. 3 Hours

Second of two courses leading to the selection, design, investigation, and completion of an independent, original Honors Thesis project under the guidance of a faculty research advisor. Restricted to students in the University Honors Program with permission of the program director and department chairperson. Students pursuing an interdisciplinary thesis topic may register for three semester hours each in two separate disciplines in consultation with the department chairpersons. Prerequisite(s): Approved 477; approval of University Honors Program.

CHM 490L. Scientific Glassblowing. 1 Hour

Theory and practice of glass working. Under the supervision of a professional glassblower, students learn to make several standard seals and fabricate pieces of glass apparatus. Enrollment limited. One three-hour laboratory each week. Grading Option Two. Prerequisite(s): Permission of department chairperson.

CHM 495. Introduction to Research Seminar. 0 Hours

Research topics presented by visiting scientists and faculty, and the results of thesis research by senior students. Required of all junior chemistry and biochemistry majors in the B.S. programs. Grading Option two.

CHM 496. Professional Practices Seminar. 0 Hours

After discussions of the chemical literature and information retrieval, resumes, graduate education, and career opportunities, students present technical talks on topics with social, ethical, or historical implications. Required of all chemistry and biochemistry majors, both B.S. and B.A.

CHM 497. Research Seminar. 0 Hours

A series of seminars as described under CHM 495. Required of all senior chemistry and biochemistry majors in the B.S. programs.

CHM 498. Research & Thesis. 3 Hours

All students in the B.S. programs including co-op students are required to enroll for a minimum of three semester hours in a research course (CHM 498). Students may take additional research semester hours (CHM 499) if the work extends for more than two semesters. Successful completion of research courses requires the submission of a typewritten thesis and the presentation of a seminar. With the prior approval of the department chairperson, B.S. co-op students may substitute work experience for research. Prerequisite(s): Permission of department chairperson.

CHM 499. Research & Thesis. 1-3 Hours

All students in the B.S. programs including co-op students are required to enroll for a minimum of three semester hours in a research course (CHM 498). Students may take additional research semester hours (CHM 499) if the work extends for more than two semesters. Successful completion of research courses requires the submission of a typewritten thesis and the presentation of a seminar. With the prior approval of the department chairperson, B.S. co-op students may substitute work experience for research. Prerequisite(s): CHM 498; permission of department chairperson.