Chemistry
Majors:
- Bachelor of Arts, Chemistry
- Bachelor of Science, Medicinal-Pharmaceutical Chemistry
- Bachelor of Science, Biochemistry
- Bachelor of Science, Chemistry
Minor:
The B.A. program in chemistry provides a framework of scientific courses which serves as a preparation for a number of interdisciplinary professions. The traditional B.S. curriculum has been modified in the B.A. program, most notably in mathematics, physics, and advanced chemistry. The program is sufficiently flexible to afford a wide selection of courses in the humanities. Science courses may be chosen to provide a preparation for professions such as medicine, dentistry, optometry, veterinary medicine, biochemistry, education, and law, as well as for employment in many other areas which require a background in science.
The B.S. program in chemistry is approved by the American Chemical Society for the training of professional chemists. Students in the B.S. program in chemistry are required to conduct an original research project. Satisfaction of this requirement normally begins with enrollment in CHM 495 and selection of a research professor and project during the second term of the junior year. The research project, conducted during the entire senior year, normally requires two work periods of three to four hours each a week. The project culminates in the final term of the senior year with enrollment in CHM 498, the submission of an acceptable thesis, and the presentation of a seminar in CHM 497. Additional research work to a maximum total of six semester hours may be elected provided that the work extends beyond two semesters. Cooperative education students may substitute work experience for research with the prior approval of the department chairperson.
The B.S. program in biochemistry follows a curriculum which satisfies the needs of students who anticipate careers in the life sciences. A mark of distinction and rigor is that each student is required to conduct research, which normally includes a ten-week summer period following their junior year and culminates with the submission of a research thesis and the presentation of a seminar.
The B.S. program in medicinal-pharmaceutical chemistry is designed to serve students who desire a more focused preparation in the analysis and synthesis of compounds of pharmacological significance. The program will also serve as a solid foundational curriculum for further studies in medicine, pharmacy or forensic chemistry. The thesis and research requirements for the degree are the same as those of the B.S. degree in chemistry, but will ordinarily involve a research experience in synthetic or analytical chemistry.
A minor in chemistry consists of twenty semester hours.
Faculty
Mark B. Masthay, Chairperson
Professors Emeriti: Fratini, Knachel, Singer
Professors: Keil, Morrow
Associate Professors: Benin, Church, Johnson, Masthay, S. Swavey
Assistant Professors: Crosson, Lopper, Mammana
Visiting Assistant Professor: Turner
Lecturer: Trick
Lab Instructors: Eckerle, Hils, Piepgrass, R. Swavey
Bachelor of Arts with a major in Chemistry (chm)
| Chemistry 1 | ||
| CHM 123 & 123L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 124 & 124L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 201 & 201L | Quantitative Anal and Quant Analysis Lab | 4 |
| CHM 302 | Physical Chemistry | 3-6 |
| or CHM 303 & CHM 304 | Physical Chemistry and Physical Chemistry | |
| CHM 313 & 313L | Organic Chemistry and Organic Chemistry Lab | 4 |
| CHM 314 & 314L | Organic Chemistry and Organic Chem Lab | 4 |
| CHM 496 | Prof Practice Seminr | 0 |
| Select four CHM electives from: 2 | 10-13 | |
| Spectro Idn-Org Cmpd | ||
| Environmental Chem | ||
| Topics-Physical Chm | ||
| Intermed Organic Chm | ||
| Analytical Chemistry | ||
| Analytical Chem Lab | ||
| Inorganic Chemistry | ||
| Inorganic Chem Lab | ||
| Biochemistry | ||
| Biosynthetic Org Chm | ||
| Medicinal Chemistry | ||
| Gen Biochemistry I | ||
| Gen Biochemistry II | ||
| Biochemistry Lab | ||
| Honors Thesis | ||
| Honors Thesis | ||
| Research & Thesis | ||
| Research & Thesis | ||
| Liberal Studies Curriculum | ||
| ASI 150 | Intr to the Univ Exp | 1 |
| PHY 201 & 201L | General Physics and General Physics Lab | 4 |
| PHY 202 & 202L | General Physics and General Physics Lab | 4 |
| Communication Competencies | 3-9 | |
| Creative and Performing Arts | 3 | |
| History | 6 | |
| L2 Proficiency (Proficiency in a language other than English) | 0-11 | |
| Literature | 3 | |
| Mathematics (excluding MTH 102, 204, 205) | 8-9 | |
| Philosophy and Religious Studies | 12 | |
| Social Sciences | 12 | |
| Total Hours - general education courses/academic electives to total at least | 124 | |
| 1 | Advanced placement is permitted. |
| 2 | May substitute two upper level courses from other science departments with permission of chairperson. |
Bachelor of Science in Medicinal-Pharmaceutical Chemistry (mcm)
| Medicinal-Pharmaceutical Chemistry 1,2 | ||
| Year 1 | ||
| CHM 123 & 123L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 124 & 124L | General Chemistry and Gen Chemistry Lab | 4 |
| Year 2 | ||
| CHM 201 & 201L | Quantitative Anal and Quant Analysis Lab | 4 |
| CHM 313 & 313L | Organic Chemistry and Organic Chemistry Lab | 4 |
| CHM 314 & 314L | Organic Chemistry and Organic Chem Lab | 4 |
| Year 3 | ||
| CHM 302 & 302L | Physical Chemistry and Physical Chem Lab 3 | 4 |
| CHM 317 | Spectro Idn-Org Cmpd | 1 |
| CHM 420 | Biochemistry 4 | 3 |
| CHM 462L | Biochemistry Lab | 1 |
| CHM 495 | Intro-Resrch Seminar | 0 |
| Year 4 | ||
| CHM 319L | Adv Org Synthsis Lab | 1 |
| CHM 426 | Biosynthetic Org Chm | 3 |
| CHM 427 | Medicinal Chemistry | 3 |
| CHM 454 | Rational Drug Design | 3 |
| CHM 463L | Bioanalytical Chem Lab | 1 |
| CHM 496 | Prof Practice Seminr | 0 |
| CHM 497 | Research Seminar | 0 |
| Science Requirements | 13 | |
| Select one course from: 5 | ||
| Intermed Organic Chm | ||
| Analytical Chemistry and Analytical Chem Lab | ||
| Inorganic Chemistry | ||
| Inorganic Chem Lab | ||
| Research & Thesis | ||
| Select two lecture courses and one laboratory from: | ||
| Physiology I and Physiology Lab | ||
| General Microbiology and Gen Microbiology Lab | ||
| Cell Biology and Cell Bio Lab | ||
| Supporting Science Requirements | ||
| BIO 151 & 151L | Concepts of Bio I and Concepts-Bio Lab I | 4 |
| BIO 152 | Concepts of Bio II | 3 |
| MTH 148 & MTH 149 | Introductory Calc I and Introductory Calc II 3 | 6 |
| MTH 367 | Statistical Meth I | 3 |
| PHY 201 & 201L | General Physics and General Physics Lab 3 | 4 |
| PHY 202 & 202L | General Physics and General Physics Lab 3 | 4 |
| Breadth Requirements | ||
| ASI 150 | Intr to the Univ Exp | 1 |
| Arts Study | 3 | |
| Communication Competencies | 3-9 | |
| History | 6 | |
| Philiosophy and Religious Studies | 12 | |
| Social and Behavioral Sciences | 6 | |
| Total Hours - general education courses/academic electives to total at least | 120 | |
| 1 | Consult General Requirements for all Bachelor of Science programs and Chapter V for General Education requirements. |
| 2 | Advanced placement is permitted. |
| 3 | Substitution of more advanced courses is possible upon consultation with the Department of Chemistry chairperson. |
| 4 | Biochemistry courses CHM 451 and CHM 452 may be substituted, with CHM 452 counting as a general elective |
| 5 | Chemistry graduate courses or advanced electives from other departments may be selected with the permission of the Department of Chemistry chairperson. |
| 6 | If composition requirement is waived, the student should select an English elective. Advanced writing courses are recommended. |
Bachelor of Science with a major in Biochemistry (bcm)
| Chemistry 1 | ||
| Year 1 | ||
| CHM 123 & 123L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 124 & 124L | General Chemistry and Gen Chemistry Lab | 4 |
| Year 2 | ||
| CHM 201 & 201L | Quantitative Anal and Quant Analysis Lab | 4 |
| CHM 313 & 313L | Organic Chemistry and Organic Chemistry Lab | 4 |
| CHM 314 & 314L | Organic Chemistry and Organic Chem Lab | 4 |
| Year 3 | ||
| CHM 303 & 303L | Physical Chemistry and Physical Chem Lab | 4 |
| CHM 304 | Physical Chemistry | 3 |
| CHM 451 | Gen Biochemistry I | 3 |
| CHM 452 | Gen Biochemistry II | 3 |
| CHM 462L | Biochemistry Lab | 1 |
| CHM 495 | Intro-Resrch Seminar | 0 |
| Year 4 | ||
| CHM 496 | Prof Practice Seminr | 0 |
| CHM 497 | Research Seminar | 0 |
| CHM 498 | Research & Thesis | 3 |
| Biology | 7 | |
| Year 1 | ||
| BIO 151 | Concepts of Bio I | 3 |
| BIO 152 & 152L | Concepts of Bio II and Concepts-Bio Lab II | 4 |
| Year 2 | ||
| BIO Elective and Laboratory | 4 | |
| Breadth Requirements | ||
| ASI 150 | Intr to the Univ Exp | 1 |
| CPS 132 | Progrmmng-Engr & Sci | 3 |
| MTH 168 | Anly Geom & Calc I | 4 |
| MTH 169 | Anly Geom & Calc II | 4 |
| MTH 218 | Anly Geom & Calc III | 4 |
| PHY 206 | Gen Physics I Mech | 3 |
| PHY 207 | Gen Phy II Ele & Mag | 3 |
| PHY 210L | Gen Physics Lab I | 1 |
| Select three courses from: | 10 | |
| General Genetics | ||
| Plant Biology | ||
| Physiology I | ||
| Physiology II | ||
| General Microbiology | ||
| Immunology | ||
| Cell Biology | ||
| Molecular Biology | ||
| Bio-Infectious Dis | ||
| Topics-Physical Chm | ||
| Intermed Organic Chm | ||
| Analytical Chemistry and Analytical Chem Lab | ||
| Inorganic Chemistry | ||
| Inorganic Chem Lab | ||
| Biosynthetic Org Chm | ||
| Medicinal Chemistry | ||
| Research & Thesis | ||
| Communication Competencies | 3-9 | |
| Foreign Language | 6-8 | |
| Humanities | 9 | |
| Philosophy and Religious Studies | 12 | |
| Social and Behavioral Sciences | 6 | |
| Total Hours - general education courses/academic electives to total at least | 120 | |
| 1 | Advanced placement is permitted. |
Bachelor of Science with a major in Chemistry (chm)
| Chemistry 1 | ||
| Year 1 | ||
| CHM 123 & 123L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 124 & 124L | General Chemistry and Gen Chemistry Lab | 4 |
| Year 2 | ||
| CHM 201 & 201L | Quantitative Anal and Quant Analysis Lab | 4 |
| CHM 313 & 313L | Organic Chemistry and Organic Chemistry Lab | 4 |
| CHM 314 & 314L | Organic Chemistry and Organic Chem Lab | 4 |
| Year 3 | ||
| CHM 303 & 303L | Physical Chemistry and Physical Chem Lab | 4 |
| CHM 304 & 304L | Physical Chemistry and Physical Chem Lab | 4 |
| CHM 317 | Spectro Idn-Org Cmpd | 1 |
| CHM 417 | Inorganic Chemistry | 3 |
| CHM 418L | Inorganic Chem Lab | 1 |
| CHM 495 | Intro-Resrch Seminar | 0 |
| Year 4 | ||
| CHM 415 & 415L | Analytical Chemistry and Analytical Chem Lab | 4 |
| CHM 420 | Biochemistry | 3 |
| or CHM 451 & CHM 452 | Gen Biochemistry I and Gen Biochemistry II | |
| CHM 496 | Prof Practice Seminr | 0 |
| CHM 497 | Research Seminar | 0 |
| CHM 498 | Research & Thesis | 3 |
| Select two CHM electives from: 2 | 6 | |
| Topics-Physical Chm | ||
| Intermed Organic Chm | ||
| Biosynthetic Org Chm | ||
| Medicinal Chemistry | ||
| Biochemistry Lab | ||
| Honors Thesis | ||
| Honors Thesis | ||
| Research & Thesis | ||
| Breadth Requirements | ||
| ASI 150 | Intr to the Univ Exp | 1 |
| PHY 206 | Gen Physics I Mech | 3 |
| PHY 207 | Gen Phy II Ele & Mag | 3 |
| PHY 208 | Gen Phy III Mec Wavs | 3 |
| PHY 210L | Gen Physics Lab I | 1 |
| PHY 211L | Gen Physics Lab II | 1 |
| Mathematics, Computer Sciences 3 | 15 | |
| Progrmmng-Engr & Sci | ||
| Anly Geom & Calc I | ||
| Anly Geom & Calc II | ||
| Anly Geom & Calc III | ||
| Communication Competencies | 3-9 | |
| Foreign Language | 6-8 | |
| Humanities | 9 | |
| Philosophy and Religious Studies | 12 | |
| Social and Behavioral Sciences | 6 | |
| Total Hours - general education courses/academic electives to total at least | 120 | |
| 1 | Advanced placement is permitted. |
| 2 | May substitute one approved science course from another department. |
| 3 | Should be completed during the first two years. |
Minor in Chemistry (chm)
| Chemistry | ||
| CHM 123 & 123L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 124 & 124L | General Chemistry and Gen Chemistry Lab | 4 |
| CHM 302 | Physical Chemistry | 3 |
| or CHM 303 | Physical Chemistry | |
| Select three CHM courses (300/400 level) 1 | 9 | |
| 1 | In consultation with the chairperson. |
Courses
CHM 115. College Prep Chm. 3 Hours
COLLEGE PREPARATORY CHEMISTRY
- One-term course for students desiring to enter a science or engineering program but whose background is insufficient for CHM 123 and CHM 124. Unacceptable for credit toward chemistry requirements in any chemistry program.
CHM 115L. College Prep Chm Lab. 1 Hour
COLLEGE PREPARATORY CHEMISTRY LABORATORY
- Course to accompany CHM 115 or to be elected by students in CHM 200 who lack previous chemistry laboratory experience. One three-hour laboratory each week.
CHM 123. General Chemistry. 3 Hours
GENERAL CHEMISTRY
- Comprehensive treatment of the fundamentals of general chemistry.
Prerequisite(s): One year of high school chemistry or equivalent.
CHM 123L. Gen Chemistry Lab. 1 Hour
GENERAL CHEMISTRY LABORATORY
- Laboratory course to complement CHM 123. One three-hour laboratory session each week.
Corequisite(s): CHM 123.
CHM 124. General Chemistry. 3 Hours
GENERAL CHEMISTRY
- Comprehensive treatment of the fundamentals of general chemistry.
Prerequisite(s): CHM 123.
CHM 124L. Gen Chemistry Lab. 1 Hour
GENERAL CHEMISTRY LABORATORY
- Laboratory course to complement CHM 124. One three-hour laboratory session each week.
Prerequisite(s): CHM 123L
Corequisite(s): CHM 124.
CHM 200. Chemistry & Society. 3 Hours
CHEMISTRY AND SOCIETY
- Course for nonscience majors. The application of chemical principles to the examination of issues such as environmental quality, disease, hunger, synthetic materials, and law enforcement. Depending upon background and experience, a student needing a laboratory course may enroll in either CHM 115L or CHM 123L.
Prerequisite(s): One year of high school chemistry or equivalent.
CHM 201. Quantitative Anal. 3 Hours
QUANTITATIVE ANALYSIS
- Application of the principles of chemical equilibrium to the theory and techniques of gravimetric, volumetric, spectrophotometric, and electroanalytical methods of chemical analysis.
Prerequisite(s): CHM 124, CHM 124L.
CHM 201L. Quant Analysis Lab. 1 Hour
QUANTITATIVE ANALYSIS LABORATORY
- Course to accompany CHM 201. One three-hour laboratory period each week.
CHM 234. Energy Resources. 3 Hours
ENERGY RESOURCES
- The chemical and geological aspects of formation, production, and benefits/costs (including environmental impacts) of energy derived from fossil fuels (coal and hydrocarbons), biofuels (e.g., ethanol production), radioactive materials (nuclear power), and renewable sources (e.g., geothermal, hydro, wind, and solar power).
Prerequisite(s): CHM 123, CHM 124.
Corequisite(s): GEO 208.
CHM 302. Physical Chemistry. 3 Hours
PHYSICAL CHEMISTRY
- Essential elements of thermodynamics, chemical kinetics, equilibria, and electrochemistry for those with a primary interest in the life sciences. For B.A. chemistry majors and premedical, predental, and biology majors.
Prerequisite(s): CHM 124.
CHM 302L. Physical Chem Lab. 1 Hour
PHYSICAL CHEMISTRY LABORATORY
- Course to accompany CHM 302. One three-hour laboratory each week.
Prerequisite(s): CHM 201, CHM 201L.
Corequisite(s): CHM 302.
CHM 303. Physical Chemistry. 3 Hours
PHYSICAL CHEMISTRY
- Fundamentals of thermodynamics, chemical kinetics, electrochemistry, and spectroscopy with a mathematics format. For B.S. chemistry and biochemistry majors and chemical engineers.
Prerequisite(s): CHM 201 or equivalent.
Corequisite(s): MTH 218.
CHM 303L. Physical Chem Lab. 1 Hour
PHYSICAL CHEMISTRY LABORATORY
- Course to accompany CHM 303. One three-hour laboratory each week.
Prerequisite(s): MTH 218.
CHM 304. Physical Chemistry. 3 Hours
PHYSICAL CHEMISTRY
- Fundamentals of thermodynamics, chemical kinetics, electrochemistry, and spectroscopy with a mathematics format. For B.S. chemistry and biochemistry majors and chemical engineers.
CHM 304L. Physical Chem Lab. 1 Hour
PHYSICAL CHEMISTRY LABORATORY
- Course to accompany CHM 304. One three-hour laboratory each week.
Corequisite(s): MTH 218.
CHM 313. Organic Chemistry. 3 Hours
ORGANIC CHEMISTRY
- Major topics in organic chemistry including synthesis, mechanisms, stereochemistry, and spectroscopy. Required of all chemistry majors and students in the life sciences.
Prerequisite(s): CHM 124.
CHM 313L. Organic Chemistry Lab. 1 Hour
ORGANIC CHEMISTRY LABORATORY
- Common separation, purification, and analytical techniques including chromatography and spectroscopy. One three-hour laboratory each week.
Corequisite(s): CHM 313.
CHM 314. Organic Chemistry. 3 Hours
ORGANIC CHEMISTRY
- Major topics in organic chemistry including synthesis, mechanisms, stereochemistry, and spectroscopy. Required of all chemistry majors and students in the life sciences.
Prerequisite(s): CHM 313.
CHM 314L. Organic Chem Lab. 1 Hour
ORGANIC CHEMISTRY LABORATORY
- Synthesis and characterization of organic materials utilizing skills from CHM 313L. One three-hour laboratory each week.
Prerequisite(s): CHM 313L.
Corequisite(s): CHM 314.
CHM 317. Spectro Idn-Org Cmpd. 1 Hour
SPECTROSCOPIC IDENTIFICATION OF ORGANIC COMPOUNDS
- The use of nuclear magnetic resonance, infrared, and mass spectrometry in elucidating structures. Emphasis on interpretation and integration of spectral data in problem solving.
Prerequisite(s): (CHM 314, CHM 314L) or equivalent.
CHM 319L. Adv Org Synthsis Lab. 1 Hour
ADVANCED ORGANIC SYNTHESIS LABORATORY
- Preparation of organic compounds by single and multi-step synthetic sequences. Basic techniques in synthesis including use of organometallics, inert atmosphere, temperature control, extraction, vacuum distillation, column chromatography, recrystallization, and spectroscopic characterization methods. One four-hour laboratory each week.
Prerequisite(s): CHM 314, CHM 314L.
CHM 341. Environmental Chem. 3 Hours
ENVIRONMENTAL CHEMISTRY
- An introduction to the chemical processes in the environment. Topics include chemical equilibrium in aqueous solution, reaction mechanisms as applied to atmospheric chemistry, and analytical methods commonly applied to environmental samples.
Prerequisite(s): CHM 314 or permission of instructor.
CHM 341L. Environmntl Chm Lab. 1 Hour
ENVIRONMENTAL CHEMISTRY LABORATORY
- Laboratory course to accompany CHM 341.
Corequisite(s): CHM 341.
CHM 404. Topics-Physical Chm. 3 Hours
SPECIAL TOPICS IN PHYSICAL CHEMISTRY
- Thorough treatment of topics such as electrochemistry, macromolecules, photochemistry, or spectroscopy. May be repeated as topics change.
Prerequisite(s): CHM 302 or CHM 303.
CHM 412. Intermed Organic Chm. 3 Hours
INTERMEDIATE ORGANIC CHEMISTRY
- Modern theory and practice of organic chemistry. May include structure-reactivity relationships, reaction mechanism, and synthetic topics not normally treated in introductory courses.
Prerequisite(s): CHM 302 or equivalent; CHM 313, CHM 314; senior standing.
CHM 415. Analytical Chemistry. 2 Hours
ANALYTICAL CHEMISTRY
- Chemical analysis based on modern instrumentation. Chromatographic, electrochemical, and spectroscopic methods.
Prerequisite(s): CHM 201, CHM 201L; (CHM 302 or CHM 304).
CHM 415L. Analytical Chem Lab. 2 Hours
ANALYTICAL CHEMISTRY LABORATORY
- Course to accompany CHM 415. Two three-hour laboratory sessions each week.
Prerequisite(s): CHM 201L; CHM 302 or equivalent.
CHM 417. Inorganic Chemistry. 3 Hours
INORGANIC CHEMISTRY
- An advanced course in modern inorganic chemistry. Atomic structure, principles of bonding and structure, acid-base chemistry, periodicity, coordination compounds, nonaqueous solvents, electrochemistry, molecular symmetry, organometallic compounds, and the chemistry of selected representative elements.
Prerequisite(s): CHM 314.
Corequisite(s): CHM 302 or CHM 304.
CHM 418L. Inorganic Chem Lab. 1 Hour
INORGANIC CHEMISTRY LABORATORY
- Laboratory course dealing with the synthesis and characterization of inorganic and organometallic compounds. Topics include vacuum and inert atmosphere techniques, separation and purification, spectroscopic characterization, X-ray diffraction, magnetic moment, and conductance measurements.
Prerequisite(s): CHM 201L, CHM 314L.
Corequisite(s): CHM 417.
CHM 420. Biochemistry. 3 Hours
BIOCHEMISTRY
- The fundamental aspects of the chemistry and biochemistry of carbohydrates, lipids, proteins, and nucleic acids. Enzymology, protein purification, bioenergetics, metabolism of carbohydrates, lipids, amino acids, nucleotides and nucleic acids, elementary molecular biology, and control processes are described. Acceptable preparation for medical school.
Prerequisite(s): CHM 314.
CHM 426. Biosynthetic Org Chm. 3 Hours
BIOSYNTHETIC ORGANIC CHEMISTRY
- Mechanistic fundamentals of the biosynthesis and transformation of organic natural products, with special emphasis on medicinal compounds, toxins, pheromones and other secondary metabolite structures.
Prerequisite(s): (CHM 314, CHM 314L) or equivalent.
CHM 427. Medicinal Chemistry. 3 Hours
MEDICINAL CHEMISTRY
- The chemical mechanisms of action of the major drug classes will be surveyed with particular emphasis on the facets of organic chemistry that control drug-receptor interactions, metabolism and mechanisms of toxicity and resistance. First term.
Prerequisite(s): CHM 314; (CHM 420 or CHM 451).
CHM 450. Adv Organic Synthesis. 3 Hours
ADVANCED ORGANIC SYNTHESIS
- Fundamentals of synthesis and transformations of organic compounds, with emphasis on mechanisms; pericyclic reactions; small and medium ring synthesis; chemoselectivity, regioselectivity, stereoselectivity, retrosynthesis, functional group transformations, carbon-carbon bond forming reactions, oxidations,
reductions and protecting groups.
Prerequisite: (CHM 314, CHM 314L) or equivalent.
CHM 451. Gen Biochemistry I. 3 Hours
GENERAL BIOCHEMISTRY I
- Discussion of the chemistry and biochemistry of carbohydrates, amino acids, proteins, and nucleic acids, including health-science and methodologic aspects. Descriptions of enzymology, protein purification, and carbohydrate metabolism related to such topics as bioenergetics, membranes, and disease processes. Recommended for students desiring entry into graduate and professional schools.
Prerequisite(s): CHM 201, CHM 314.
CHM 452. Gen Biochemistry II. 3 Hours
GENERAL BIOCHEMISTRY II
- Discussion of selected topics in bioenergetics, and metabolism of lipids, amino acids, porphyrins, nucleic acids, and proteins. Current aspects of nutrition, biochemical genetics, endocrinology, regulation, and genetic engineering addressed and related to health-science topics as time permits. Suitable preparation for medical school.
Prerequisite(s): CHM 451.
CHM 454. Rational Drug Design. 3 Hours
RATIONAL DRUG DESIGN
- Introduction to drug target selection, lead compound discovery, and application of structure-activity relationships and computational chemistry towards refinement and optimization of lead compounds and their derivatives. Use of molecular graphics software and publicly available macromolecular structure databases will provide the foundation for evaluating macromolecular models of drug targets and allow a hands-on exploration of the structure/function relationships of proteins that have been successful targets of rational drug design.
Prerequisite(s): (CHM 420 or CHM 452) or equivalent.
CHM 462L. Biochemistry Lab. 1 Hour
BIOCHEMISTRY LABORATORY
- Laboratory course to accompany biochemistry lecture courses. Spectrophotometry, pH and dissociation, enzymologic methodology and analytical techniques, chromatographic techniques.
Corequisite(s): CHM 420 or CHM 451.
CHM 463L. Bioanalytical Chem Lab. 1 Hour
BIOANALYTICAL CHEMISTRY LABORATORY
- Introduction to analytical methods in current use in biochemistry. Course will focus on separations and spectroscopic methods for the analysis of biomolecules.
Prerequisite(s): CHM 201, CHM 201L, CHM 302.
CHM 477. Honors Thesis. 3 Hours
HONORS THESIS PROJECT
- First of two courses leading to the selection, design, investigation, and completion of an independent, original Honors Thesis project under the guidance of a faculty research advisor. Restricted to students in the University Honors Program with permission of the program director and department chairperson. Students pursuing an interdisciplinary thesis topic may register for three semester hours each in two separate disciplines in consultation with the department chairpersons.
Prerequisite(s): Approval of University Honors Program.
CHM 478. Honors Thesis. 3 Hours
HONORS THESIS PROJECT
- Second of two courses leading to the selection, design, investigation, and completion of an independent, original Honors Thesis project under the guidance of a faculty research advisor. Restricted to students in the University Honors Program with permission of the program director and department chairperson. Students pursuing an interdisciplinary thesis topic may register for three semester hours each in two separate disciplines in consultation with the department chairpersons.
Prerequisite(s): Approved 477; approval of University Honors Program.
CHM 490L. Scientifc Glassblowing. 1 Hour
SCIENTIFIC GLASSBLOWING
- Theory and practice of glass working. Under the supervision of a professional glassblower, students learn to make several standard seals and fabricate pieces of glass apparatus. Enrollment limited. One three-hour laboratory each week. Grading Option Two.
Prerequisite(s): Permission of department chairperson.
CHM 495. Intro-Resrch Seminar. 0 Hours
INTRODUCTION TO RESEARCH SEMINAR
- Research topics presented by visiting scientists and faculty, and the results of thesis research by senior students. Required of all junior chemistry and biochemistry majors in the B.S. programs. Grading Option two.
CHM 496. Prof Practice Seminr. 0 Hours
PROFESSIONAL PRACTICES SEMINAR
- After discussions of the chemical literature and information retrieval, resumes, graduate education, and career opportunities, students present technical talks on topics with social, ethical, or historical implications. Required of all chemistry and biochemistry majors, both B.S. and B.A.
CHM 497. Research Seminar. 0 Hours
RESEARCH SEMINAR
A - series of seminars as described under CHM 495. Required of all senior chemistry and biochemistry majors in the B.S. programs.
CHM 498. Research & Thesis. 3 Hours
RESEARCH AND THESIS
- All students in the B.S. programs including co-op students are required to enroll for a minimum of three semester hours in a research course (CHM 498). Students may take additional research semester hours (CHM 499) if the work extends for more than two semesters. Successful completion of research courses requires the submission of a typewritten thesis and the presentation of a seminar. With the prior approval of the department chairperson, B.S. co-op students may substitute work experience for research.
Prerequisite(s): Permission of department chairperson.
CHM 499. Research & Thesis. 1-3 Hours
RESEARCH AND THESIS
- All students in the B.S. programs including co-op students are required to enroll for a minimum of three semester hours in a research course (CHM 498). Students may take additional research semester hours (CHM 499) if the work extends for more than two semesters. Successful completion of research courses requires the submission of a typewritten thesis and the presentation of a seminar. With the prior approval of the department chairperson, B.S. co-op students may substitute work experience for research.
Prerequisite(s): CHM 498; permission of department chairperson.

